DNA N4-methylcytosine (4mC) modification occurs mainly in prokaryotic DNA.

We proposed a new identification method nemed SOMM4mC based on a Markov model which makes use of the transition probability between adjacent nucleotides to identify 4mC site.

The results show that our algorithm is superior to the other three algorithms in all six species (C.elegans, D.melanogaster, A.thaliana, E.coli, G.subterruneus, and G.pickeringii).

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